LjaFGD


Enzyme information


Ubiquitin mediated proteolysis


Protein KO Enzyme Annotation
GWHPAAZE011369 K02977 RP-S27Ae, RPS27A, UBA80 ubiquitin-small subunit ribosomal protein S27Ae
GWHPAAZE011389 K02977 RP-S27Ae, RPS27A, UBA80 ubiquitin-small subunit ribosomal protein S27Ae
GWHPAAZE012340 K02977 RP-S27Ae, RPS27A, UBA80 ubiquitin-small subunit ribosomal protein S27Ae
GWHPAAZE022300 K02977 RP-S27Ae, RPS27A, UBA80 ubiquitin-small subunit ribosomal protein S27Ae
GWHPAAZE022944 K02977 RP-S27Ae, RPS27A, UBA80 ubiquitin-small subunit ribosomal protein S27Ae
GWHPAAZE000636 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE001624 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE001630 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE005050 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE011515 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE011516 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE011548 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE011550 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE011551 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE014771 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE018324 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE029058 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE029059 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE030217 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE033213 K03094 SKP1, CBF3D S-phase kinase-associated protein 1
GWHPAAZE000630 K03178 UBE1, UBA1 ubiquitin-activating enzyme E1 [EC:6.2.1.45]
GWHPAAZE005382 K03178 UBE1, UBA1 ubiquitin-activating enzyme E1 [EC:6.2.1.45]
GWHPAAZE009377 K03178 UBE1, UBA1 ubiquitin-activating enzyme E1 [EC:6.2.1.45]
GWHPAAZE031112 K03178 UBE1, UBA1 ubiquitin-activating enzyme E1 [EC:6.2.1.45]
GWHPAAZE031113 K03178 UBE1, UBA1 ubiquitin-activating enzyme E1 [EC:6.2.1.45]
GWHPAAZE031114 K03178 UBE1, UBA1 ubiquitin-activating enzyme E1 [EC:6.2.1.45]
GWHPAAZE026576 K03348 APC1 anaphase-promoting complex subunit 1
GWHPAAZE026577 K03348 APC1 anaphase-promoting complex subunit 1
GWHPAAZE026578 K03348 APC1 anaphase-promoting complex subunit 1
GWHPAAZE026579 K03348 APC1 anaphase-promoting complex subunit 1
GWHPAAZE026580 K03348 APC1 anaphase-promoting complex subunit 1
GWHPAAZE013509 K03349 APC2 anaphase-promoting complex subunit 2
GWHPAAZE004450 K03350 APC3, CDC27 anaphase-promoting complex subunit 3
GWHPAAZE006586 K03351 APC4 anaphase-promoting complex subunit 4
GWHPAAZE001736 K03352 APC5 anaphase-promoting complex subunit 5
GWHPAAZE027123 K03353 APC6, CDC16 anaphase-promoting complex subunit 6
GWHPAAZE022132 K03354 APC7 anaphase-promoting complex subunit 7
GWHPAAZE030587 K03355 APC8, CDC23 anaphase-promoting complex subunit 8
GWHPAAZE007448 K03357 APC10, DOC1 anaphase-promoting complex subunit 10
GWHPAAZE012651 K03363 CDC20 cell division cycle 20, cofactor of APC complex
GWHPAAZE027987 K03363 CDC20 cell division cycle 20, cofactor of APC complex
GWHPAAZE027988 K03363 CDC20 cell division cycle 20, cofactor of APC complex
GWHPAAZE003212 K03364 CDH1 cell division cycle 20-like protein 1, cofactor of APC complex
GWHPAAZE006156 K03364 CDH1 cell division cycle 20-like protein 1, cofactor of APC complex
GWHPAAZE022827 K03869 CUL3 cullin 3
GWHPAAZE024316 K03869 CUL3 cullin 3
GWHPAAZE024150 K03875 SKP2, FBXL1 F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
GWHPAAZE001478 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE003663 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE003680 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE007029 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE012731 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE024833 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE025266 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE031524 K04506 SIAH1 E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
GWHPAAZE017238 K04554 UBE2J2, NCUBE2, UBC6 ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
GWHPAAZE031159 K04554 UBE2J2, NCUBE2, UBC6 ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
GWHPAAZE017656 K04649 HIP2, UBC1 ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
GWHPAAZE030798 K04649 HIP2, UBC1 ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
GWHPAAZE006012 K04706 PIAS1 E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
GWHPAAZE001317 K06688 UBE2C, UBC11 ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
GWHPAAZE009134 K06688 UBE2C, UBC11 ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
GWHPAAZE000565 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE003008 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE005305 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE005980 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE005981 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE009448 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE014964 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE018332 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE027380 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE027527 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE031484 K06689 UBE2D, UBC4, UBC5 ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
GWHPAAZE021883 K08770 UBC ubiquitin C
GWHPAAZE009542 K09561 STUB1, CHIP STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
GWHPAAZE009346 K10140 DDB2 DNA damage-binding protein 2
GWHPAAZE002417 K10143 RFWD2, COP1 E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
GWHPAAZE003540 K10143 RFWD2, COP1 E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
GWHPAAZE004886 K10143 RFWD2, COP1 E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
GWHPAAZE005681 K10144 RCHY1, PIRH2 RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
GWHPAAZE009058 K10144 RCHY1, PIRH2 RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
GWHPAAZE009061 K10144 RCHY1, PIRH2 RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
GWHPAAZE009863 K10144 RCHY1, PIRH2 RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
GWHPAAZE022126 K10144 RCHY1, PIRH2 RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
GWHPAAZE025990 K10144 RCHY1, PIRH2 RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
GWHPAAZE025993 K10144 RCHY1, PIRH2 RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
GWHPAAZE018821 K10456 KLHL19, KEAP1, INRF2 kelch-like protein 19
GWHPAAZE018822 K10456 KLHL19, KEAP1, INRF2 kelch-like protein 19
GWHPAAZE016409 K10570 ERCC8, CKN1, CSA DNA excision repair protein ERCC-8
GWHPAAZE027882 K10571 DET1 de-etiolated-1
GWHPAAZE017846 K10573 UBE2A, UBC2, RAD6A ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
GWHPAAZE030628 K10573 UBE2A, UBC2, RAD6A ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
GWHPAAZE033192 K10573 UBE2A, UBC2, RAD6A ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
GWHPAAZE033196 K10573 UBE2A, UBC2, RAD6A ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
GWHPAAZE000773 K10575 UBE2G1, UBC7 ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
GWHPAAZE004974 K10575 UBE2G1, UBC7 ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
GWHPAAZE005550 K10575 UBE2G1, UBC7 ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
GWHPAAZE026701 K10575 UBE2G1, UBC7 ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
GWHPAAZE017904 K10576 UBE2H, UBC8 ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
GWHPAAZE024892 K10576 UBE2H, UBC8 ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
GWHPAAZE025295 K10576 UBE2H, UBC8 ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
GWHPAAZE031428 K10576 UBE2H, UBC8 ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
GWHPAAZE033253 K10576 UBE2H, UBC8 ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
GWHPAAZE014130 K10577 UBE2I, UBC9 ubiquitin-conjugating enzyme E2 I
GWHPAAZE014624 K10577 UBE2I, UBC9 ubiquitin-conjugating enzyme E2 I
GWHPAAZE023416 K10577 UBE2I, UBC9 ubiquitin-conjugating enzyme E2 I
GWHPAAZE012295 K10578 UBE2J1, NCUBE1, UBC6 ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
GWHPAAZE022249 K10578 UBE2J1, NCUBE1, UBC6 ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
GWHPAAZE014823 K10579 UBE2M, UBC12 ubiquitin-conjugating enzyme E2 M
GWHPAAZE016542 K10579 UBE2M, UBC12 ubiquitin-conjugating enzyme E2 M
GWHPAAZE018484 K10579 UBE2M, UBC12 ubiquitin-conjugating enzyme E2 M
GWHPAAZE002063 K10580 UBE2N, BLU, UBC13 ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
GWHPAAZE002636 K10580 UBE2N, BLU, UBC13 ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
GWHPAAZE027135 K10580 UBE2N, BLU, UBC13 ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
GWHPAAZE002180 K10581 UBE2O ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
GWHPAAZE002697 K10581 UBE2O ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
GWHPAAZE004668 K10581 UBE2O ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
GWHPAAZE006626 K10581 UBE2O ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
GWHPAAZE018321 K10581 UBE2O ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
GWHPAAZE007268 K10583 UBE2S, E2EPF ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
GWHPAAZE007269 K10583 UBE2S, E2EPF ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
GWHPAAZE005718 K10588 UBE3B ubiquitin-protein ligase E3 B [EC:2.3.2.26]
GWHPAAZE005721 K10588 UBE3B ubiquitin-protein ligase E3 B [EC:2.3.2.26]
GWHPAAZE005722 K10588 UBE3B ubiquitin-protein ligase E3 B [EC:2.3.2.26]
GWHPAAZE013170 K10590 TRIP12 E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
GWHPAAZE018337 K10590 TRIP12 E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
GWHPAAZE030208 K10590 TRIP12 E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
GWHPAAZE014415 K10597 UBE4B, UFD2 ubiquitin conjugation factor E4 B [EC:2.3.2.27]
GWHPAAZE033121 K10597 UBE4B, UFD2 ubiquitin conjugation factor E4 B [EC:2.3.2.27]
GWHPAAZE023494 K10598 PPIL2, CYC4, CHP60 peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
GWHPAAZE011545 K10599 PRPF19, PRP19 pre-mRNA-processing factor 19 [EC:2.3.2.27]
GWHPAAZE012640 K10601 SYVN1, HRD1 E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
GWHPAAZE014710 K10606 FANCL, PHF9 E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
GWHPAAZE004576 K10609 CUL4 cullin 4
GWHPAAZE006705 K10609 CUL4 cullin 4
GWHPAAZE006706 K10609 CUL4 cullin 4
GWHPAAZE006820 K10610 DDB1 DNA damage-binding protein 1
GWHPAAZE017680 K10684 UBLE1A, SAE1 ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
GWHPAAZE030092 K10685 UBLE1B, SAE2, UBA2 ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
GWHPAAZE021600 K10686 UBE1C, UBA3 ubiquitin-activating enzyme E1 C [EC:6.2.1.45]
GWHPAAZE021608 K10686 UBE1C, UBA3 ubiquitin-activating enzyme E1 C [EC:6.2.1.45]
GWHPAAZE013953 K10688 UBE2W, UBC16 ubiquitin-conjugating enzyme E2 W [EC:2.3.2.25]
GWHPAAZE013954 K10688 UBE2W, UBC16 ubiquitin-conjugating enzyme E2 W [EC:2.3.2.25]
GWHPAAZE014899 K10688 UBE2W, UBC16 ubiquitin-conjugating enzyme E2 W [EC:2.3.2.25]
GWHPAAZE008378 K20217 UBE2E ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]


Pathway information

map04120